RUNX3 and melanoma: It should be noted that miR-330-5p targets RUNX family transcription factor 3 (RUNX3), which seems to be responsible for the regulation of BCL2L11 (BIM) transcription, regulation of I-kappaB kinase/NF-kappaB signaling, and signaling by NOTCH in melanoma cells (Feng et al., 2022[15]).