Finally, to determine if these in vitro generated TAMs could be reprogrammed to a less immunosuppressive anti-tumour phenotype, TAMs were treated with LPS/IFNγ overnight and co-cultured with T cells for four days prior to assessment of T cell proliferation; LPS/IFNγ treatment significantly alleviated TAM suppression of T cell proliferation (Figure 2F). Here, IFNG is linked to neoplasm.