The number of patients with abnormal tumor biomarkers before radical cystectomy were as follows: 7 (1.9%) with abnormal CEA, 18 (4.9%) with abnormal β-hCG, 19 (5.1%) with abnormal CA125, and 29 (7.9%) with abnormal CA19-9 (Table 1). Here, MUC16 is linked to neoplasm.