For example, in triple-negative breast cancer (TNBC), the most aggressive molecular subtype, miR-200b suppresses metastasis by targeting Rho GTPase-activating protein 18 (ARHGAP18) and promoting RhoA activation (Humphries et al., 2017), underscoring the critical role of miR-200b in BC progression. This evidence concerns the gene ARHGAP18 and triple-negative breast carcinoma.