PARK7 and Parkinson disease: Moreover, the pole test was also used to detect defects in motor coordination for other PD mouse models, and studies consistently confirmed absence of detectable motor deficits in PD models such as the Parkin (Perez and Palmiter, 2005; Pinto et al., 2018), LRRK2 (Xiong et al., 2017; Adeosun et al., 2017), and DJ-1 (Kim et al., 2005; Chandran et al., 2008).