Classical MAPKs, including ERK1/2 (MAPK3/1), JNK1‐3 (MAPK8‐10), p38 (MAPK11‐14), and ERK5 (MAPK7), have been proven to be activated by shear stress and predominantly participate in atherosclerosis progression.9, 10, 11. This evidence concerns the gene MAPK7 and atherosclerosis.