HMOX2 mRNA was evidently m1A de‐methylated in the MeRIP‐seq data and downregulated in RNA‐seq data after TRMT61A knockdown, and overexpressed in human BLCA tissues; the same result was obtained with The Cancer Genome Atlas (TCGA) database (Figure 2B,C and Figure S2E). Here, TRMT61A is linked to bladder transitional cell carcinoma.