Using samples from BLCA patients, a positive correlation was observed between HMOX2 and TRMT61A expression; HMOX2 expression decreased in tumour tissues from mice xenografted with TRMT61A shRNA and increased in tumour tissues from BBN‐driven urinary BLCA mice (Figures S2H–K and S3). This evidence concerns the gene HMOX2 and bladder transitional cell carcinoma.