To further explore the potential oncogenic role of POSTN in SCLC, immunohistochemical (IHC) staining of SCLC patient tissue array was performed, revealing a high protein abundance of POSTN in stage III, indicative of a strong correlation between POSTN and SCLC malignancy (Fig. 1G-H) in the cohort (Supplementary Table S1). This evidence concerns the gene POSTN and small cell lung carcinoma.