In the other published report of a patient transplanted with RIPK1-deficiency, few details were given: the molecular diagnosis was made post-mortem; the patient was said to have been symptomatic with recurrent infections from birth and received a matched-family donor HSCT at 12 months of age; the graft failed and she was re-transplanted using the same donor at 3 years 2 months; she eventually died aged 19 years from chronic GVHD and ‘pulmonary disease’ [7]. The gene discussed is RIPK1; the disease is infection.