CD8A and pleural neoplasm: The patient had pleural target lesions with the sum of the longest diameters (of baseline tumors) (SLD) at 108 mm, which was reduced to 10 mm after 13 months on treatment (Fig. 5d); 2.5% of tumor-infiltrating lymphocytes in the biopsy taken 5 months after start of treatment from a regressing pleural tumor lesion were autogene cevumeran-specific CD8+ T cells (Fig. 3h).