Although the result showed the copy number of EGFR/ERBB2 showed a worse prognosis than the low copy number patients, the results showed no statistical significance between the copy number of EGFR/ERBB2 and the prognosis of ampullary adenocarcinoma (Supplementary Fig. S2o, p). The gene discussed is ERBB2; the disease is ampulla of vater adenocarcinoma.