CD40LG and microcephaly: Consistent with the low positivity rate in most of the cases (Figs 2A, B and S1A), we did not observe significant differences in ZIKV or DENV IgM-NS1 in the mothers of children with microcephaly versus those without microcephaly, both in terms of the positivity rate (Fig 3A), or the relative plasma levels (Fig 3B).