Other inflammatory markers such as α-1-acid glycoproteins have also been found to be robust markers of inflammation and in one study comparing the performance of CRP and an α-1-acid glycoprotein signal, measured using nuclear magnetic resonance (NMR) spectroscopy (GlycA), CRP was more closely associated with obesity, whereas GlycA was a better risk predictor for cardiovascular disease [10]. This evidence concerns the gene CRP and obesity due to melanocortin 4 receptor deficiency.