The disease associations in OMIM for these genes also revealed that 38% were hereditary cancer predisposition syndromes (e.g., VHL associated with von Hippel-Lindau syndrome) and 62% were not known to include cancer as a predominant feature (e.g., FGFR3 associated with Achondroplasia) [26]. This evidence concerns the gene FGFR3 and cancer.