QTRT1 and urinary tract infection: tgt transcription is repressed by CRP and slightly induced by tobramycin in V. cholerae tgt was previously observed to be upregulated in E. coli isolates from urinary tract infection (Bielecki et al., 2014) and in V. cholerae after mitomycin C treatment (through indirect SOS induction; Krin et al., 2018).