The prevalence of positivity against each isoform of IFN-α was similar in participants with recent-onset T1D when compared to people with longer T1D duration (P > .99 for AAb-IFN-α1, P = .28 for AAb-IFN-α2, and P = .73 for AAb-IFN-α14; Supplementary Fig. S3C-E) (16). Here, IFNA2 is linked to type 1 diabetes mellitus.