Clots from patients with concomitant cancer had a significantly higher content of vWF (median 26 [IQR13‐38]% vs. 10 [4–18]%, p < 0.0001) and H3Cit (median 0.11 [IQR0.02–0.46]% vs. 0.05 [0.00–0.28]% p = 0.027) than controls. This evidence concerns the gene VWF and cancer.