FGFR2 and Pfeiffer syndrome: About 20% of craniosynostosis cases have a genetic basis, often due to autosomal dominant FGFR (Fibroblast growth factor receptor) mutations-FGFR1 in Pfeiffer's syndrome and FGFR2 in Apert’s and Crouzon’s syndromes [4]. Non-inherited mutations, as observed in our case, account for approximately 50% of cases.