POMC and precocious puberty: Some cases have reported the production of ectopic adrenocorticotropic hormone (ACTH), parathyroid hormone-related peptide (PTHRP), and beta-human chorionic gonadotropin (hCG), presenting with a paraneoplastic presentation of precocious puberty, which is speculated to be related to the ectopic beta-hCG secretion [3-9].