TP53, SMAD4, NOTCH1, ERBB2 (HER2), PIK3CA, MET, PTEN, ATM, NTRK1, CDKN2A/B, STK11, EGFR, KRAS, BRAF, CTNNB1, NRAS, CCNE1, tumor mutational burden, and MSI. This evidence concerns the gene PIK3CA and neoplasm.