CD40LG and infection: At this point, the number of peripheral blood IgM+ B cells increased gradually starting with the group that received the highest dose of 2,500,000 parasites followed by the group receiving ten times less, until IgM+ B cell counts were four-fold that of the control group on day 41 in the 6th week of infection, the timepoint when we previously observed a peak of B cell expansion (26).