Research has found that both Esculentoside A and dexamethasone (positive controls) significantly alleviate asthma reactions, including airway inflammation, eosinophil migration to the lungs, excessive mucus secretion, and a decrease in Th2 cytokines and IgE, while enhancing antioxidant capacity by increasing the levels of SOD, CAT, and GSH. Here, IGHE is linked to asthma.