Women are more likely to develop AD than men (Alzheimer’s Disease International, 2018), with a 19–29% higher incidence rate (ADI, n.d.), possibly due to women having a higher Tau protein load (Buckley et al., 2019; Babapour Mofrad et al., 2020), measured at higher levels of AD pathology (Oveisgharan et al., 2018; Biechele et al., 2024). The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.