CD8A and neoplasm: When we stained CD8+ T cells along with in situ TUNEL (terminal deoxynucleotidyl transferase–mediated deoxyuridine triphosphate nick end labeling) staining, we observed impaired infiltration of tumors with CD8+ T cells and a decreased number of TUNEL-positive tumor cells in tumors from Ppp2cafl/fl/dLckcre mice (Fig. S2C).