RAG1 and neoplasm: To get rid of the complex effect from other T cells and precisely ascertain the role of PP2A in CD8+ T cells [18–20], naïve CD8+ T cells were isolated from WT and Ppp2cafl/fl/dLckcre mice and subsequently adoptively transferred into immunodeficient Rag1−/− recipient mice, which were then subjected to a tumor challenge (Fig. S2G).