The pathological analysis led to a diagnosis of PSP (Fig. 1A, B), as demonstrated by positive immunostaining for epithelial membrane antigen (EMA), thyroid transcription factor-1 (TTF-1), and cytokeratin (CK) AE1/AE3 (Fig. 1C–E), with prominent round stromal cell proliferation and pleomorphism compared to normal tissue. Here, MUC1 is linked to supranuclear palsy, progressive, 1.