SLC1A5 and SLC7A5 are targets of c‐Myc.[44, 45] c‐Myc knockdown led to the reduced expression of SLC1A5/SLC3A2/SLC7A5 and ISR activation in ESCC cells (Figure S7D, Supporting Information). This evidence concerns the gene SLC7A5 and esophageal squamous cell carcinoma.