Consistent with the RTN4IP1 expression pattern in the ESCC proteomic study (Figure S1B, Supporting Information), subsequent analysis of RTN4IP1 expression in the TCGA database using UALCAN (http://ualcan.path.uab.edu/)[21] and a microarray study of ESCC[22] confirmed augmented RTN4IP1 mRNA levels in tumors (Figure 1B,C). The gene discussed is RTN4IP1; the disease is esophageal squamous cell carcinoma.