TIMP3 is increased in several cardiovascular diseases (Mukherjee et al. 2006; Polyakova et al. 2011), while uncontrollable expression of VEGF‐A (similar to neovascular AMD) has been linked to higher risk and worsened severity of cardiovascular diseases (Cho et al. 2006; Meng et al. 2009). The gene discussed is VEGFA; the disease is cardiovascular disorder.