NFKB1 and COVID-19: Single-cell sequencing and RNA-sequencing studies conducted on peripheral blood mononuclear cells and bronchoalveolar immune cells from COVID-19 patients have consistently demonstrated that SARS-CoV-2 infection triggers robust activation of the NF-κB pathway.299–302 Despite these findings, the precise mechanisms through which SARS-CoV-2 induces NF-κB activation are still uninvestigated.