G3BP1 and viral infectious disease: At this time, zinc ions and RNA also assist in the formation of LLPS from G3BP1-cGAS.247 In addition, during the early stages of viral infection when these primary condensates are formed, ZYG11B also binds to cGAS along with G3BP1 to form large droplets, concentrating the relatively low concentration of cGAS in the droplets and increasing its sensitivity to dsDNA.