Recent studies have identified iCAF in several tumour types, including pancreatic cancer and breast cancer [5, 6, 17, 38], using a variety of markers that encompass inflammatory cytokines and other genes (CXCL1, CXCL8, CXCL12, IL6, CFD, DPT) [5]. This evidence concerns the gene CFD and familial pancreatic carcinoma.