In contrast to the increased pro-tumour phenotype of macrophages after chemotherapy, CXCL13+CD8+T cells (tumour-reactive CD8+T cells) exhibited elevated cytotoxicity, inflammation, and activation scores after chemotherapy (Figs. S2A–C), which is in line with the elevated antigen presentation scores in dendritic cells after chemotherapy (Figs. S2D–F). This evidence concerns the gene CXCL13 and neoplasm.