Additionally, the public data showed that ALDOA mRNA was upregulated in colorectal adenoma (P < 0.01, Fig. 1B), and was further elevated in colorectal adenocarcinoma (P < 0.001, Fig. 1B), suggesting the progressive elevation of ALDOA expression from adenoma to adenocarcinoma. Here, ALDOA is linked to colorectal adenocarcinoma.