The levels of DG (20:2n6/0:0/22:2n6), DG (2:0/0:0/0:0), DG (16:1/20:4/0:0), DG (13:0/0:0/0:0), DG(15:0/0:0/20:2), DG (16:1/0:0/20:4), DG (18:1n9/0:0/20:3n6), PE (18:1/P-18:0), PE (14:1/14:1), PE (20:4/P-16:0), PE (14:0/18:0), PE (20:0/24:1), SM (d19:0/20:3), PC (24:0/22:6), Cer (d16:1/20:4), were significantly lower in the PD group than in the control group. The gene discussed is CBLN1; the disease is Parkinson disease.