In this study, we assembled a large set ofsmall compounds withknown affinities toward Galectin-3 and -1 (Gal-3 and -1), which aresugar-binding proteins that play a role in various pathological conditionsincluding inflammation, cancer, pulmonary fibrosis, or viral entry.45,46 The resulting ligand set contains more than a thousand ligands with Kd values obtained from fluorescence anisotropyassay and thus represents the largest set of galectin inhibitors usablefor in silico evaluations and one of the largest curated ligand setsagainst a single target. The gene discussed is LGALS3; the disease is pulmonary fibrosis.