Interestingly, cytokines that positively regulate CD8+ T‐cell activation and promote tumour infiltration and cytotoxicity of CD8+ effector T cells, such as ICAM1,33 CXCL934 and CCL3,35 were increased in the FMD+2‐DG+anti‐PD‐1 group. This evidence concerns the gene CD8A and neoplasm.