Subsequently, coculture with EDEM3OE CRC cells significantly inhibited T‐cell‐mediated tumour killing as indicated by an increased percentage of viable cells (Figure 2F,G and Figure S3D–G) and attenuated IFN‐γ and IL‐2 secretion in the corresponding samples (Figure 2H and Figure S3H). This evidence concerns the gene IFNG and colorectal carcinoma.