From the literature, we observed that Peptostreptococcus anaerobius interacted with integrin α2β1 in CRC and promoted CXCL1 secretion by activating NF‐κB, with the latter interacting with C‐X‐C chemokine receptor type 2 (CXCR2) on myeloid‐derived suppressor cells (MDSCs), thereby promoting MDSC migration, reducing functional T cell infiltration and creating an immunosuppressive microenvironment conducive to CRC.56 This evidence concerns the gene NFKB1 and colorectal carcinoma.