In the OLP group, mRNA expression levels of EGF, EGFR, PDGF‐β, PDGFR‐β and HIF1A genes were found to be 0.726, 1.235, 0.329, 1.002 and 0.623, respectively, when compared to the control group. The gene discussed is EGFR; the disease is oral lichen planus.