Furthermore, YAP with TEADs enhances Jagged1-Notch1 signaling; Notch1 promotes YAP stability through inhibited β-TrCP-mediated degradation and formation of a YAP1- jagged-1/Notch1-positive feedback loop in breast cancer cells (Zhao et al., 2022). This evidence concerns the gene NOTCH1 and breast carcinoma.