In contrast, protein O-linked mannose Protein O-Mannosyltransferase 2 (POMGNT2) (OR = 0.62, 95% CI 0.41–0.91, P = 0.017) and C–C motif chemokine 14 (CCL14) (OR = 0.80, 95% CI 0.67–0.94, P = 0.011) were associated with a reduced risk of CLL (Fig. 3). This evidence concerns the gene CCL14 and B-cell chronic lymphocytic leukemia.