Furthermore, for DNTs (namely CD45+/CD3+/CD4−/CD8− T lymphocytes; DNTs were not analyzed in the GBM IDHwt tumors) immunostaining also confirmed evidence of DNTs in all the analyzed IDHmut diffuse astrocytoma and oligodendroglioma tumors (Supplementary Fig. 7). The gene discussed is PTPRC; the disease is diffuse astrocytoma.