CD4 and neoplasm: On the other hand, elevated percentages of FAP +  cells exhibited significant positive correlations with higher percentages of CD4 + (tumor center, Spearman’s Rho = 0.24, p = 0.026; tumor periphery, Spearman’s Rho = 0.237; p = 0.03), CD8 + (tumor center, Spearman’s Rho = 0.524, p < 0.001; tumor periphery, Spearman’s Rho = 0.374; p < 0.001), CD4 + FOXP3 + (tumor center, Spearman’s Rho = 0.486, p < 0.001; tumor periphery, Spearman’s Rho = 0.281; p = 0.01), and CD68 +  cells (tumor center, Spearman’s Rho = 0.239, p = 0.237; tumor periphery, Spearman’s Rho = 0.528, p < 0.001).