IL6 and periodontitis: A study in 2022, conducted by Balasubramaniam, discovered a significant number of diabetic individuals with chronic periodontitis having possible chances of developing cognitive impairment.14Another study suggests that the risk of cognitive impairment may increase by high IL-6 levels.15This study aimed to explore the effects of antibiotic periodontal treatment on MCI risk through the changes in protein plasma from blood samples assessment in T2DM patients.