One hundred six (22%) participants had a concomitant active sexually transmitted infection (STI), and 220 (43%) had a history of human immunodeficiency virus (HIV)/AIDS diagnosis, of whom 210 (95%) were on antiretroviral treatment; their median CD4 T-cell count at last follow-up was 743 cells/μL with 19 of 188 (10%) having CD4 <350 cells/μL. This evidence concerns the gene CD4 and sexually transmitted disease.