To investigate whether enhancing Dexras1 S‐nitrosylation hinders functional recovery from stroke, we generated an AAV vector expressing Dexras1 (AAV‐Dexras1‐GFP‐3Flag) and its control AAV‐GFP‐3Flag, infused them into the peri‐infarct cortex of mice immediately after stroke and found that AAV‐Dexras1‐GFP‐3Flag effectively infected the peri‐infarct cortex (Figure 4A), produced Dexras1‐GFP‐3Flag fusion proteins (Figure 4B), and significantly enhanced levels of Dexras1 (including endogenous and exogenous Dexras1) and SNO‐Dexras1 at 7 d after the infection (Figure 4C–E). The gene discussed is RASD1; the disease is stroke disorder.