IL18 and polycystic ovary syndrome: Additionally, elevated levels of inflammatory factors, such as high sensitive C-reactive protein (hs-CRP), interleukin-18 (IL-18), tumor necrosis factor α (TNF-α), interleukin-6 (IL-6), monocyte chemoattractant protein-1 (MCP-1), and macrophage inflammatory protein-1α (MIP-1α), are detected in the peripheral blood of PCOS patients (9, 18), indicating the presence of SLCI (Table 1).