Simultaneously, the expression of both inflammation-related genes (CCL-2, IL-6, TNF-α, induced protein 6 [TNFAIP6] and pro-oncogenic genes (cell adhesion molecule with homology to L1CAM [CHL1]) is upregulated in the endometrium of PCOS patients than in controls (62). The gene discussed is CCL2; the disease is polycystic ovary syndrome.