TEK and Schnyder corneal dystrophy: Plasma mean Tie-2 levels were, however, lower in HbSS (2,009 ± 512.2 pg/mL) than in HbAA (3,988 ± 1,398 pg/mL, p = 0.0005), suggesting dysregulated angiogenesis in SCD (Figures 7G, I, J, M–Q).