CYP/LOX: ↑ 5-, 8-, 11-, 12-, 15-, 19-, 20-, HETELOX: ↑LTD4, TXA2↓ PGsSignificantly associated with hypertension:11-dehydro-2,3-dinor-TXB2, 12-HHTrE, 295.2279/4.89 (putative eicosanoid), 5,6-EET, Tetranor-12(R)-HETE. The gene discussed is LOX; the disease is hypertensive disorder.