INS and Insulin resistance: For instance, primary hepatocytes have been employed to assess the impact of Inositol polyphosphate multikinase on FFAs-induced insulin resistance (57), to evaluate the role of chemotactic eicosanoid LTB4 in dexamethasone-induced insulin resistance (58), as well as to determine the insulin sensitization effect of short-term curcumin gavage in a rapid dexamethasone-induced insulin resistance (59).