Table 1 showed that CIND and dementia were older (P < 0.001), more likely to be an ApoE carrier (P = 0.001), had fewer years of education (P < 0.001), higher systolic blood pressure (P = 0.045, and higher prevalence of hypertension (P < 0.001) and diabetes (P = 0.002) compared to the NCI group. This evidence concerns the gene APOE and Hypertension.