Other benefits include reduction of chilblains (Meesilpavikkai et al. 2019), pericardial effusion (Casas-Alba et al. 2022), and IFN gene expression (Sanchez et al. 2018; Kanazawa et al. 2023; Ryckmans et al. 2024; Galli et al. 2023; Meesilpavikkai et al. 2019; Casas-Alba et al. 2022). This evidence concerns the gene IFNA1 and pericardial effusion.