PROX2 and liver disorder: In addition, state #5 was identified as PDPN, FOXC2, and PROX2-expressing lymphatic-specific ECs; state #6 as a subpopulation expressing PLAT, whose protein level is increased in patients with liver disease (Leiper et al, 1994); and, states #23, #32 and #34 as liver-specific liver sinusoidal ECs (LSECs).